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What are common consequences of diabetes?

2013/11/2      view:
Over time, diabetes can damage the heart, blood vessels, eyes, kidneys, and nerves.
  • Diabetes increases the risk of heart disease and stroke. 50% of people with diabetes die of cardiovascular disease (primarily heart disease and stroke) (6).
  • Combined with reduced blood flow, neuropathy (nerve damage) in the feet increases the chance of foot ulcers, infection and eventual need for limb amputation.
  • Diabetic retinopathy is an important cause of blindness, and occurs as a result of long-term accumulated damage to the small blood vessels in the retina.  One percent of global blindness can be attributed to diabetes (7).
  • Diabetes is among the leading causes of kidney failure (4).
  • The overall risk of dying among people with diabetes is at least double the risk of their peers without diabetes (8).
 

    References

    (1) Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet, 2011, 378(9785):31–40.
    (2) Global health risks. Mortality and burden of disease attributable to selected major risks. Geneva, World Health Organization, 2009.
    (3) Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med, 2006, 3(11):e442.
    (4) Global status report on noncommunicable diseases 2010. Geneva, World Health Organization, 2011.
    (5)    Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Geneva, World Health Organization, 1999 (WHO/NCD/NCS/99.2).
    (6) Morrish NJ, Wang SL, Stevens LK, Fuller JH, Keen H. Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 2001, 44 Suppl 2:S14–S21.
    (7) Global data on visual impairments 2010. Geneva, World Health Organization, 2012.
    (8) Roglic G, Unwin N, Bennett PH, Mathers C, Tuomilehto J, Nag S et al. The burden of mortality attributable to diabetes: realistic estimates for the year 2000. Diabetes Care, 2005, 28(9):2130–2135.

 
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